2021
Testicular adenosine acts as a pro-inflammatory molecule: role of testicular peritubular cells.Missel A, Walenta L, Eubler K, Mundt N, Heikelä H, Pickl U, Trottmann M, Popper B, Poutanen M, Strauss L, Köhn FM, Kunz L, Spehr M, Mayerhofer A.Mol Hum Reprod. 2021 May 16:gaab037. doi: 10.1093/molehr/gaab037. Online ahead of print.PMID: 33993290
Exploring the Ion Channel TRPV2 and Testicular Macrophages in Mouse Testis.Eubler K, Rantakari P, Gerke H, Herrmann C, Missel A, Schmid N, Walenta L, Lahiri S, Imhof A, Strauss L, Poutanen M, Mayerhofer A.Int J Mol Sci. 2021 Apr 29;22(9):4727. doi: 10.3390/ijms22094727.PMID: 33946947
Comparative Analysis of the Effects of Long-Term 3,5-diiodothyronine Treatment on the Murine Hepatic Proteome and Transcriptome Under Conditions of Normal Diet and High-Fat Diet.Lietzow J, Golchert J, Pietzner M, Völker U, Poutanen M, Ohlsson C, Homuth G, Köhrle J.Thyroid. 2021 Apr 7. doi: 10.1089/thy.2020.0160. Online ahead of print.PMID: 33637021
Docetaxel chemotherapy response in PC3 prostate cancer mouse model detected by rotating frame relaxations and water diffusion.Laakso H, Ylä-Herttuala E, Sierra A, Jambor I, Poutanen M, Liljenbäck H, Virtanen H, Merisaari H, Aronen H, Minn H, Roivainen A, Liimatainen T.NMR Biomed. 2021 Apr;34(4):e4483. doi: 10.1002/nbm.4483. Epub 2021 Feb 4.PMID: 33543563
Correction: MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility.Lahiri S, Aftab W, Walenta L, Strauss L, Poutanen M, Mayerhofer A, Imhof A.Life Sci Alliance. 2021 Jan 21;4(3):e202101015. doi: 10.26508/lsa.202101015. Print 2021 Mar.PMID: 33479050
MALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility.Lahiri S, Aftab W, Walenta L, Strauss L, Poutanen M, Mayerhofer A, Imhof A.Life Sci Alliance. 2021 Jan 6;4(3):e202000672. doi: 10.26508/lsa.202000672. Print 2021 Mar.PMID: 33408244
Statistical Evaluation of Different Mathematical Models for Diffusion Weighted Imaging of Prostate Cancer Xenografts in Mice.Merisaari H, Laakso H, Liljenbäck H, Virtanen H, Aronen HJ, Minn H, Poutanen M, Roivainen A, Liimatainen T, Jambor I.Front Oncol. 2021 May 26;11:583921. doi: 10.3389/fonc.2021.583921. eCollection 2021.PMID: 3412377
AMP-activated protein kinase (AMPK) signaling in GnRH neurons links energy status and reproduction.Franssen D, Barroso A, Ruiz-Pino F, Vázquez MJ, García-Galiano D, Castellano JM, Onieva R, Ruiz-Cruz M, Poutanen M, Gaytán F, Diéguez C, Pinilla L, Lopez M, Roa J, Tena-Sempere M.Metabolism. 2021 Feb;115:154460. doi: 10.1016/j.metabol.2020.154460. Epub 2020 Dec 4.PMID: 33285180
2020
Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice. Aguilar-Pimentel JA, Cho YL, Gerlini R, Calzada-Wack J, Wimmer M, Mayer-Kuckuk P, Adler T, Schmidt-Weber CB, Busch DH, Fuchs H, Gailus-Durner V, Ollert M, Hrabě de Angelis M, Ohlsson C, Poutanen M, Teperino R, Strauss L. Sci Rep. 2020 Oct 27;10(1):18334. doi: 10.1038/s41598-020-75059-9.PMID: 33110090
Interplay between gonadal hormones and postnatal overfeeding in defining sex-dependent differences in gut microbiota architecture. Santos-Marcos JA, Barroso A, Rangel-Zuñiga OA, Perdices-Lopez C, Haro C, Sanchez-Garrido MA, Molina-Abril H, Ohlsson C, Perez-Martinez P, Poutanen M, Lopez-Miranda J, Perez-Jimenez F, Tena-Sempere M, Camargo A. Aging (Albany NY). 2020 Oct 27;12(20):19979-20000. doi: 10.18632/aging.104140. Epub 2020 Oct 27.PMID: 33107844
Phosphorylation site S122 in estrogen receptor α has a tissue-dependent role in female mice. Ohlsson C, Gustafsson KL, Farman HH, Henning P, Lionikaite V, Movérare-Skrtic S, Sjögren K, Törnqvist AE, Andersson A, Islander U, Bernardi AI, Poutanen M, Chambon P, Lagerquist MK. FASEB J. 2020 Dec;34(12):15991-16002. doi: 10.1096/fj.201901376RR. Epub 2020 Oct 16.PMID: 33067917
Genetic Ablation of MiR-22 Fosters Diet-Induced Obesity and NAFLD Development. Gjorgjieva M, Sobolewski C, Ay AS, Abegg D, Correia de Sousa M, Portius D, Berthou F, Fournier M, Maeder C, Rantakari P, Zhang FP, Poutanen M, Picard D, Montet X, Nef S, Adibekian A, Foti M. J Pers Med. 2020 Oct 14;10(4):170. doi: 10.3390/jpm10040170.PMID: 33066497
Erbb4 regulates the oocyte microenvironment during folliculogenesis. Veikkolainen V, Ali N, Doroszko M, Kiviniemi A, Miinalainen I, Ohlsson C, Poutanen M, Rahman N, Elenius K, Vainio SJ, Naillat F. Hum Mol Genet. 2020 Oct 10;29(17):2813-2830. doi: 10.1093/hmg/ddaa161.PMID: 32716031
Neonatal exposure to androgens dynamically alters gut microbiota architecture. Barroso A, Santos-Marcos JA, Perdices-Lopez C, Vega-Rojas A, Sanchez-Garrido MA, Krylova Y, Molina-Abril H, Ohlsson C, Perez-Martinez P, Poutanen M, Lopez-Miranda J, Tena-Sempere M, Camargo A. J Endocrinol. 2020 Oct;247(1):69-85. doi: 10.1530/JOE-20-0277.PMID: 32755996
A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions. Gabriel M, Fey V, Heinosalo T, Adhikari P, Rytkönen K, Komulainen T, Huhtinen K, Laajala TD, Siitari H, Virkki A, Suvitie P, Kujari H, Aittokallio T, Perheentupa A, Poutanen M. Sci Data. 2020 Aug 28;7(1):284. doi: 10.1038/s41597-020-00623-x.PMID: 32859947
Glycovariant-based lateral flow immunoassay to detect ovarian cancer-associated serum CA125. Bayoumy S, Hyytiä H, Leivo J, Talha SM, Huhtinen K, Poutanen M, Hynninen J, Perheentupa A, Lamminmäki U, Gidwani K, Pettersson K. Commun Biol. 2020 Aug 21;3(1):460. doi: 10.1038/s42003-020-01191-x.PMID: 32826955
Role of kisspeptins in the control of the hypothalamic-pituitary-ovarian axis: old dogmas and new challenges. Ruohonen ST, Poutanen M, Tena-Sempere M. Fertil Steril. 2020 Sep;114(3):465-474. doi: 10.1016/j.fertnstert.2020.06.038. Epub 2020 Aug 6.PMID: 32771258
Hydroxysteroid (17β) dehydrogenase 12 is essential for metabolic homeostasis in adult mice. Heikelä H, Ruohonen ST, Adam M, Viitanen R, Liljenbäck H, Eskola O, Gabriel M, Mairinoja L, Pessia A, Velagapudi V, Roivainen A, Zhang FP, Strauss L, Poutanen M. Am J Physiol Endocrinol Metab. 2020 Sep 1;319(3):E494-E508. doi: 10.1152/ajpendo.00042.2020. Epub 2020 Jul 21.PMID: 32691632
Transcriptomic responses to hypoxia in endometrial and decidual stromal cells. Rytkönen KT, Heinosalo T, Mahmoudian M, Ma X, Perheentupa A, Elo LL, Poutanen M, Wagner GP. Reproduction. 2020 Jul;160(1):39-51. doi: 10.1530/REP-19-0615.PMID: 32272449
Exploratory Analysis of CA125-MGL and -STn Glycoforms in the Differential Diagnostics of Pelvic Masses. Salminen L, Nadeem N, Rolfsen AL, Dørum A, Laajala TD, Grènman S, Hietanen S, Heinosalo T, Perheentupa A, Poutanen M, Bolstad N, Carpén O, Lamminmäki U, Pettersson K, Gidwani K, Hynninen J, Huhtinen K. J Appl Lab Med. 2020 Mar 1;5(2):263-272. doi: 10.1093/jalm/jfz012.PMID: 32445385
Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer. Tiwari R, Manzar N, Bhatia V, Yadav A, Nengroo MA, Datta D, Carskadon S, Gupta N, Sigouros M, Khani F, Poutanen M, Zoubeidi A, Beltran H, Palanisamy N, Ateeq B. Nat Commun. 2020 Jan 20;11(1):384. doi: 10.1038/s41467-019-14184-0.PMID: 31959826
2019
The gut microbiota is a major regulator of androgen metabolism in intestinal contents. Colldén H, Landin A, Wallenius V, Elebring E, Fändriks L, Nilsson ME, Ryberg H, Poutanen M, Sjögren K, Vandenput L, Ohlsson C. Am J Physiol Endocrinol Metab. 2019 Dec 1;317(6):E1182-E1192. doi: 10.1152/ajpendo.00338.2019. Epub 2019 Nov 5.PMID: 31689143
Europium Nanoparticle-Based Sialyl-Tn Monoclonal Antibody Discriminates Epithelial Ovarian Cancer-Associated CA125 from Benign Sources. Gidwani K, Nadeem N, Huhtinen K, Kekki H, Heinosalo T, Hynninen J, Perheentupa A, Poutanen M, Carpen O, Pettersson K, Lamminmäki U. J Appl Lab Med. 2019 Nov;4(3):299-310. doi: 10.1373/jalm.2018.028266. Epub 2019 Aug 23.PMID: 31659068
Personalized Drug Sensitivity Screening for Bladder Cancer Using Conditionally Reprogrammed Patient-derived Cells. Kettunen K, Boström PJ, Lamminen T, Heinosalo T, West G, Saarinen I, Kaipio K, Rantala J, Albanese C, Poutanen M, Taimen P. Eur Urol. 2019 Oct;76(4):430-434. doi: 10.1016/j.eururo.2019.06.016. Epub 2019 Jun 28.PMID: 31256944
Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis.Velasco I, León S, Barroso A, Ruiz-Pino F, Heras V, Torres E, León M, Ruohonen ST, García-Galiano D, Romero-Ruiz A, Sánchez-Garrido MA, Olhsson C, Castellano JM, Roa J, Poutanen M, Pinilla L, Vázquez MJ, Tena-Sempere M. Metabolism. 2019 Sep;98:84-94. doi: 10.1016/j.metabol.2019.06.007. Epub 2019 Jun 19.PMID: 31226351
Interleukin-6 in the central amygdala is bioactive and co-localised with glucagon-like peptide-1 receptor. Anesten F, Dalmau Gasull A, Richard JE, Farkas I, Mishra D, Taing L, Zhang F, Poutanen M, Palsdottir V, Liposits Z, Skibicka KP, Jansson JO. J Neuroendocrinol. 2019 Jun;31(6):e12722. doi: 10.1111/jne.12722. Epub 2019 May 23.PMID: 31033078
Applying mass spectrometric methods to study androgen biosynthesis and metabolism in prostate cancer. Knuuttila M, Hämäläinen E, Poutanen M. J Mol Endocrinol. 2019 May 1;62(4):R255-R267. doi: 10.1530/JME-18-0150.PMID: 30917337
Biology and clinical relevance of Hydroxysteroid (17beta) dehydrogenase enzymes. Poutanen M, Penning TM. Mol Cell Endocrinol. 2019 Jun 1;489:1-2. doi: 10.1016/j.mce.2019.04.008. Epub 2019 Apr 13.PMID: 30991077
Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction. Zhang FP, Malinen M, Mehmood A, Lehtiniemi T, Jääskeläinen T, Niskanen EA, Korhonen H, Laiho A, Elo LL, Ohlsson C, Kotaja N, Poutanen M, Sipilä P, Palvimo JJ. Nat Commun. 2019 Feb 15;10(1):777. doi: 10.1038/s41467-019-08730-z.PMID: 30770815
Glucagon-Like Peptide-1-, but not Growth and Differentiation Factor 15-, Receptor Activation Increases the Number of Interleukin-6-Expressing Cells in the External Lateral Parabrachial Nucleus. Anesten F, Mishra D, Dalmau Gasull A, Engström-Ruud L, Bellman J, Palsdottir V, Zhang F, Trapp S, Skibicka KP, Poutanen M, Jansson JO. Neuroendocrinology. 2019;109(4):310-321. doi: 10.1159/000499693. Epub 2019 Mar 20.PMID: 30889580
Simultaneous analysis by LC-MS/MS of 22 ketosteroids with hydroxylamine derivatization and underivatized estradiol from human plasma, serum and prostate tissue. Häkkinen MR, Murtola T, Voutilainen R, Poutanen M, Linnanen T, Koskivuori J, Lakka T, Jääskeläinen J, Auriola S. J Pharm Biomed Anal. 2019 Feb 5;164:642-652. doi: 10.1016/j.jpba.2018.11.035. Epub 2018 Nov 16.PMID: 30472582
2018
Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling. Roa J, Barroso A, Ruiz-Pino F, Vázquez MJ, Seoane-Collazo P, Martínez-Sanchez N, García-Galiano D, Ilhan T, Pineda R, León S, Manfredi-Lozano M, Heras V, Poutanen M, Castellano JM, Gaytan F, Diéguez C, Pinilla L, López M, Tena-Sempere M. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10758-E10767. doi: 10.1073/pnas.1802053115. Epub 2018 Oct 22.PMID: 30348767
Decidualization of Human Endometrial Stromal Fibroblasts is a Multiphasic Process Involving Distinct Transcriptional Programs. Rytkönen KT, Erkenbrack EM, Poutanen M, Elo LL, Pavlicev M, Wagner GP. Reprod Sci. 2019 Mar;26(3):323-336. doi: 10.1177/1933719118802056. Epub 2018 Oct 11.PMID: 30309298
Hyperthyroidism and Papillary Thyroid Carcinoma in Thyrotropin Receptor D633H Mutant Mice. Jaeschke H, Undeutsch H, Patyra K, Löf C, Eszlinger M, Khalil M, Jännäri M, Makkonen K, Toppari J, Zhang FP, Poutanen M, Paschke R, Kero J. Thyroid. 2018 Oct;28(10):1372-1386. doi: 10.1089/thy.2018.0041.PMID: 30132406
Adrenals Contribute to Growth of Castration-Resistant VCaP Prostate Cancer Xenografts. Huhtaniemi R, Oksala R, Knuuttila M, Mehmood A, Aho E, Laajala TD, Nicorici D, Aittokallio T, Laiho A, Elo L, Ohlsson C, Kallio P, Mäkelä S, Mustonen MVJ, Sipilä P, Poutanen M. Am J Pathol. 2018 Dec;188(12):2890-2901. doi: 10.1016/j.ajpath.2018.07.029. Epub 2018 Sep 28.PMID: 30273606
Androgen receptor SUMOylation regulates bone mass in male mice.Wu J, Movérare-Skrtic S, Zhang FP, Koskela A, Tuukkanen J, Palvimo JJ, Sipilä P, Poutanen M, Ohlsson C. Mol Cell Endocrinol. 2019 Jan 5;479:117-122. doi: 10.1016/j.mce.2018.09.008. Epub 2018 Sep 24.PMID: 30261210
Role of hydroxysteroid (17beta) dehydrogenase type 1 in reproductive tissues and hormone-dependent diseases. Heinosalo T, Saarinen N, Poutanen M. Mol Cell Endocrinol. 2019 Jun 1;489:9-31. doi: 10.1016/j.mce.2018.08.004. Epub 2018 Aug 25.PMID: 30149044
NLRP3 in somatic non-immune cells of rodent and primate testes. Walenta L, Schmid N, Schwarzer JU, Köhn FM, Urbanski HF, Behr R, Strauss L, Poutanen M, Mayerhofer A. Reproduction. 2018 Sep;156(3):231-238. doi: 10.1530/REP-18-0111. Epub 2018 Jun 15.PMID: 29907661
Preface. Poutanen M, Tena-Sempere M. Best Pract Res Clin Endocrinol Metab. 2018 Jun;32(3):215-218. doi: 10.1016/j.beem.2018.05.001.PMID: 29779577
Partial thyrocyte-specific Gαs deficiency leads to rapid-onset hypothyroidism, hyperplasia, and papillary thyroid carcinoma-like lesions in mice. Patyra K, Jaeschke H, Löf C, Jännäri M, Ruohonen ST, Undeutsch H, Khalil M, Kero A, Poutanen M, Toppari J, Chen M, Weinstein LS, Paschke R, Kero J. FASEB J. 2018 May 25:fj201800211R. doi: 10.1096/fj.201800211R. Online ahead of print.PMID: 29799790
Intratumoral androgen levels are linked to TMPRSS2-ERG fusion in prostate cancer. Knuuttila M, Mehmood A, Mäki-Jouppila J, Ryberg H, Taimen P, Knaapila J, Ettala O, Boström PJ, Ohlsson C, Venäläinen MS, Laiho A, Elo LL, Sipilä P, Mäkelä SI, Poutanen M. Endocr Relat Cancer. 2018 Sep;25(9):807-819. doi: 10.1530/ERC-18-0148. Epub 2018 May 17.PMID: 29773553
Secreted frizzled-related protein 2 (SFRP2) expression promotes lesion proliferation via canonical WNT signaling and indicates lesion borders in extraovarian endometriosis. Heinosalo T, Gabriel M, Kallio L, Adhikari P, Huhtinen K, Laajala TD, Kaikkonen E, Mehmood A, Suvitie P, Kujari H, Aittokallio T, Perheentupa A, Poutanen M. Hum Reprod. 2018 May 1;33(5):817-831. doi: 10.1093/humrep/dey026.PMID: 29462326
Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult mice. Ohlsson C, Henning P, Nilsson KH, Wu J, Gustafsson KL, Sjögren K, Törnqvist A, Koskela A, Zhang FP, Lagerquist MK, Poutanen M, Tuukkanen J, Lerner UH, Movérare-Skrtic S.J Endocrinol. 2018 May;237(2):113-122. doi: 10.1530/JOE-18-0020. Epub 2018 Mar 12.PMID: 29530924
WNT16 overexpression partly protects against glucocorticoid-induced bone loss. Ohlsson C, Nilsson KH, Henning P, Wu J, Gustafsson KL, Poutanen M, Lerner UH, Movérare-Skrtic S. Am J Physiol Endocrinol Metab. 2018 Jun 1;314(6):E597-E604. doi: 10.1152/ajpendo.00292.2017. Epub 2018 Feb 6.PMID: 29406783
Analysis by LC-MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue. Häkkinen MR, Heinosalo T, Saarinen N, Linnanen T, Voutilainen R, Lakka T, Jääskeläinen J, Poutanen M, Auriola S. J Pharm Biomed Anal. 2018 Apr 15;152:165-172. doi: 10.1016/j.jpba.2018.01.034. Epub 2018 Jan 31.PMID: 29414008
Hydroxysteroid (17β) dehydrogenase 13 deficiency triggers hepatic steatosis and inflammation in mice. Adam M, Heikelä H, Sobolewski C, Portius D, Mäki-Jouppila J, Mehmood A, Adhikari P, Esposito I, Elo LL, Zhang FP, Ruohonen ST, Strauss L, Foti M, Poutanen M. FASEB J. 2018 Jun;32(6):3434-3447. doi: 10.1096/fj.201700914R. Epub 2018 Jan 31.PMID: 29401633
HSD17B1 expression induces inflammation-aided rupture of mammary gland myoepithelium. Järvensivu P, Heinosalo T, Hakkarainen J, Kronqvist P, Saarinen N, Poutanen M. Endocr Relat Cancer. 2018 Apr;25(4):393-406. doi: 10.1530/ERC-17-0476. Epub 2018 Jan 25.PMID: 29371331
Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria. Hilander T, Zhou XL, Konovalova S, Zhang FP, Euro L, Chilov D, Poutanen M, Chihade J, Wang ED, Tyynismaa H. Nucleic Acids Res. 2018 Jan 25;46(2):849-860. doi: 10.1093/nar/gkx1231.PMID: 29228266
Hydroxysteroid (17β) dehydrogenase 1 expressed by Sertoli cells contributes to steroid synthesis and is required for male fertility. Hakkarainen J, Zhang FP, Jokela H, Mayerhofer A, Behr R, Cisneros-Montalvo S, Nurmio M, Toppari J, Ohlsson C, Kotaja N, Sipilä P, Poutanen M. FASEB J. 2018 Jun;32(6):3229-3241. doi: 10.1096/fj.201700921R. Epub 2018 Jan 24.PMID: 29401623
The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer. Kemiläinen H, Huhtinen K, Auranen A, Carpén O, Strauss L, Poutanen M. Oncology. 2018;94(4):233-242. doi: 10.1159/000485624. Epub 2018 Jan 12.PMID: 29324448
2017
Deleting the mouse Hsd17b1 gene results in a hypomorphic Naglu allele and a phenotype mimicking a lysosomal storage disease. Jokela H, Hakkarainen J, Kätkänaho L, Pakarinen P, Ruohonen ST, Tena-Sempere M, Zhang FP, Poutanen M. Sci Rep. 2017 Nov 27;7(1):16406. doi: 10.1038/s41598-017-16618-5.PMID: 29180785
Antiandrogens Reduce Intratumoral Androgen Concentrations and Induce Androgen Receptor Expression in Castration-Resistant Prostate Cancer Xenografts. Knuuttila M, Mehmood A, Huhtaniemi R, Yatkin E, Häkkinen MR, Oksala R, Laajala TD, Ryberg H, Handelsman DJ, Aittokallio T, Auriola S, Ohlsson C, Laiho A, Elo LL, Sipilä P, Mäkelä SI, Poutanen M. Am J Pathol. 2018 Jan;188(1):216-228. doi: 10.1016/j.ajpath.2017.08.036. Epub 2017 Nov 7.PMID: 29126837
Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development. Sankar A, Kooistra SM, Gonzalez JM, Ohlsson C, Poutanen M, Helin K. Development. 2017 Sep 15;144(18):3264-3277. doi: 10.1242/dev.155473. Epub 2017 Aug 21.PMID: 28827393
Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty. Elo T, Lindfors PH, Lan Q, Voutilainen M, Trela E, Ohlsson C, Huh SH, Ornitz DM, Poutanen M, Howard BA, Mikkola ML. Sci Rep. 2017 Jul 11;7(1):5049. doi: 10.1038/s41598-017-04637-1.PMID: 28698625
Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice. Ohlsson C, Hammarstedt A, Vandenput L, Saarinen N, Ryberg H, Windahl SH, Farman HH, Jansson JO, Movérare-Skrtic S, Smith U, Zhang FP, Poutanen M, Hedjazifar S, Sjögren K. Am J Physiol Endocrinol Metab. 2017 Oct 1;313(4):E450-E462. doi: 10.1152/ajpendo.00093.2017. Epub 2017 Jun 27.PMID: 28655716
Matched preclinical designs for improved translatability.Aittokallio T, Scherer A, Poutanen M, Freedman LP. Sci Transl Med. 2017 May 10;9(389):eaal4101. doi: 10.1126/scitranslmed.aal4101.PMID: 28490671
Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency. Heinonen J, Zhang FP, Surmann-Schmitt C, Honkala S, Stock M, Poutanen M, Säämänen AM. Osteoarthritis Cartilage. 2017 Jul;25(7):1132-1142. doi: 10.1016/j.joca.2017.03.010. Epub 2017 Mar 18.PMID: 28323137