Other Affiliations

• Institute of Clinical Medicine Department of Obstetrics and Gynecology

Selected Publications

Heinosalo T, Rytkönen KT, Saarinen N, Järvensivu P, Damdimopoulou P, Strauss L, Orasniemi S, Horshauge P, Gabriel M, Koskimies P, Ohlsson C, Kronqvist P, Poutanen M. Overexpression of Human Estrogen Biosynthetic Enzyme Hydroxysteroid (17beta) Dehydrogenase Type 1 Induces Adenomyosis-like Phenotype in Transgenic Mice. International Journal of Molecular Sciences. 2022; 23(9):4815.

Strauß T, Greve B, Gabriel M, Achmad N, Schwan D, Espinoza-Sanchez NA, Laganà AS, Kiesel L, Poutanen M, Götte M, Schäfer SD. Impact of Musashi-1 and Musashi-2 Double Knockdown on Notch Signaling and the Pathogenesis of Endometriosis. International Journal of Molecular Sciences. 2022; 23(5):2851.

Gabriel M, Fey V, Heinosalo T, Adhikari P, Rytkönen K, Komulainen T, Huhtinen K, Laajala TD, Siitari H, Virkki A, Suvitie P, Kujari H, Aittokallio T, Perheentupa A, Poutanen M: A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions. Sci Data. 2020 Aug 28;7(1):284.

Heikelä H, Ruohonen ST, Adam M, Viitanen R, Liljenbäck H, Eskola O, Gabriel M, Mairinoja L, Pessia A, Velagapudi V, Roivainen A, Zhang F, Strauss L, Poutanen M. Hydroxysteroid (17β) dehydrogenase 12 is essential for the metabolic homeostasis in adult mice. American Journal of Physiology – Endocrinology and Metabolism 2020 Jul 21. doi: 10.1152/ajpendo.00042.2020.

Heinosalo T, Gabriel M, Kallio L, Adhikari P, Huhtinen K, Laajala D, Kaikkonen E, Mehmood A, Suvitie P, Kujari H, Aittokallio T, Perheentupa A, Poutanen M: Human SFRP2 marks endometriosis lesion borders and acts as a canonical WNT signaling agonist promoting proliferation of endometriosis lesions. Hum Reprod. 2018 May 1;33(5):817-831.

Järvensivu P, Saloniemi-Heinonen T, Awosanya M, Koskimies P, Saarinen N, Poutanen M: HSD17B1 expression enhances estrogen signaling stimulated by the low active estrone, evidenced by an estrogen responsive element-driven reporter gene in vivo. Chem Biol Interact. 2015 Jun 5;234:126-34.

Huhtinen K, Saloniemi-Heinonen T, Keski-Rahkonen P, Desai R, Laajala D, Ståhle M, Häkkinen MR, Awosanya M, Suvitie P, Kujari H, Aittokallio T, Handelsman DJ, Auriola S, Perheentupa A, Poutanen M: Intra-tissue steroid profiling indicates differential progesterone and testosterone metabolism in the endometrium and endometriosis lesions. J Clin Endocrinol Metab. 2014 Nov;99(11):E2188-97.